NAC supplies N-acetyl-L-cysteine, a derivative of L-Cysteine, which is more stable and better absorbed than L-Cysteine. NAC functions as a potent antioxidant. As the precursor to glutathione intracellular synthesis, it is essential for the synthesis of glutathione. Glutathione is a critical component of the immune system, as it is an important intracellular water-soluble antioxidant. As part of this function, glutathione plays a vital role as the cofactor for the antioxidant enzymes glutathione peroxidase and glutathione transferase. Glutathione is also important to the liver, as the liver utilizes it for drug detoxification. As a metabolite of cysteine, NAC plays an important role in detoxification, and is hepatoprotective. NAC functions in protecting cells against oxidative stress, and contributes to important bodily reactions. As such it is a part of the defensive mechanism toward potential carcinogens, as well as against DNA damage. The role of NAC in acetaminophen toxicity is widely documented, however, NAC contributes to other protective mechanisms as well, including drug conjugation and excretion, peroxide and free radical destruction, maintenance of the redox state of NADPH-NADP, acid-base balance, and the synthesis of sulfated compounds. NAC also plays a role in the development of the central nervous system. There have been numerous studies using NAC, with COPD, particularly amongst patients who smoke. Utilizing NAC in smokers with chronic bronchitis showed a significant reduction in the number of positive bacterial cultures in these patients. {Riise GC, et al. Eur Respir J.1994 Jan; 7(1):94-101.} Another study utilizing NAC indicated potential benefits for chronic bronchitis, resulting in a significantly lower exacerbation rate in patients administered NAC, compared to placebo. {Rassmussen, JB & Glennow, C. Eur Respir J. 1988 Apr;1(4):351-5.} Since it easily passes through cellular membranes, NAC has been shown to be readily absorbed. It is also resistant to enzymatic breakdown.

Bio-C Plus 1000™ supplies Vitamin C (as calcium and magnesium ascorbates), along with calcium and magnesium as mineral ascorbates, in addition to citrus bioflavonoids (citrus fruit), Superoxide Dismutase (from vegetable culture), and Catalase (from vegetable culture). At higher dosages mixed ascorbates are less likely to cause digestive distress as compared to ascorbic acid. Use wherever the need for vitamin C is determined.

EGCG, an important catechin supplied as a green tea extract, possesses significant antioxidant activity and provides related neuroprotective action, and has been shown to support normal, healthy cardiovascular and immune function.

Zn-Zyme Forte™ supplies 25 mg of elemental zinc per tablet. Zinc is a mineral essential to both normal health and to optimal cellular function. As a cofactor for an excess of seventy enzymes, zinc plays an important role in many cellular processes. Zinc is also a component of specific DNA binding proteins, known as zinc finger proteins, commonly referred to as zinc fingers. Zinc fingers are vital for nutrient/gene interactions. Consider Zn-Zyme Forte™ when a higher level of zinc supplemental is indicated.

Selenomethionine, an organic form of selenium, is a readily absorbable form of this essential trace mineral. Selenium functions as an integral part of glutathione peroxidase, an important antioxidant enzyme, and is required for normal thyroid function.

Bio-DK-Mulsion™ supplies 125 mcg (5,000 IU) of vitamin D3 and 300 mcg of vitamin K (as K1 phytonadione and K2 menaquinone-7) in a micro-emulsion for enhanced absorption and utilization, which is particularly important for those with malabsorption conditions. Clinical data shows that the emulsified form increases bioavailability over 200% compared to the non-emulsified form. In addition, Bio-DK-Mulsion™ is absorbed first through the lymphatic system, the body's preferred route of administration, and then transported to the blood circulation.